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Ras isoform abundance and signalling in human cancer cell lines

The ubiquitously expressed major Ras isoforms: H-, K- and N-Ras, are highly conserved, yet exhibit different biological outputs. We have compared the relative efficiencies with which EGF or HGF activate Ras isoforms and the requirement for specific isoforms in the activation of downstream pathways....

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Bibliografski detalji
Glavni autori: Omerovic, Jasminka, Hammond, Dean E., Clague, Michael J., Prior, Ian A.
Format: Artigo
Jezik:Inglês
Izdano: 2007
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2557550/
https://ncbi.nlm.nih.gov/pubmed/17998936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.onc.1210925
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