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Ras isoform abundance and signalling in human cancer cell lines
The ubiquitously expressed major Ras isoforms: H-, K- and N-Ras, are highly conserved, yet exhibit different biological outputs. We have compared the relative efficiencies with which EGF or HGF activate Ras isoforms and the requirement for specific isoforms in the activation of downstream pathways....
Sparad:
| Huvudupphovsmän: | , , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
2007
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2557550/ https://ncbi.nlm.nih.gov/pubmed/17998936 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.onc.1210925 |
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