Absolute Quantification of Endogenous Ras Isoform Abundance

Ras proteins are important signalling hubs situated near the top of networks controlling cell proliferation, differentiation and survival. Three almost identical isoforms, HRAS, KRAS and NRAS, are ubiquitously expressed yet have differing biological and oncogenic properties. In order to help underst...

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Udgivet i:PLoS One
Main Authors: Mageean, Craig J., Griffiths, John R., Smith, Duncan L., Clague, Michael J., Prior, Ian A.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4641634/
https://ncbi.nlm.nih.gov/pubmed/26560143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0142674
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