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Absolute Quantification of Endogenous Ras Isoform Abundance

Ras proteins are important signalling hubs situated near the top of networks controlling cell proliferation, differentiation and survival. Three almost identical isoforms, HRAS, KRAS and NRAS, are ubiquitously expressed yet have differing biological and oncogenic properties. In order to help underst...

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Publicat a:PLoS One
Autors principals: Mageean, Craig J., Griffiths, John R., Smith, Duncan L., Clague, Michael J., Prior, Ian A.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4641634/
https://ncbi.nlm.nih.gov/pubmed/26560143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0142674
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