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Decoding RAS isoform and codon-specific signalling
RAS proteins are key signalling hubs that are oncogenically mutated in 30% of all cancer cases. Three genes encode almost identical isoforms that are ubiquitously expressed, but are not functionally redundant. The network responses associated with each isoform and individual oncogenic mutations rema...
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| Publié dans: | Biochem Soc Trans |
|---|---|
| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Portland Press Ltd.
2014
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4961500/ https://ncbi.nlm.nih.gov/pubmed/25109951 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BST20140057 |
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