Spatiotemporal Regulation of ERK2 by Dual Specificity Phosphatases

Although many stimuli activate extracellular signal-regulated kinases 1 and 2 (ERK1/2), the kinetics and compartmentalization of ERK1/2 signals are stimulus-dependent and dictate physiological consequences. ERKs can be inactivated by dual specificity phosphatases (DUSPs), notably the MAPK phosphatas...

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Bibliographische Detailangaben
Hauptverfasser: Caunt, Christopher J., Armstrong, Stephen P., Rivers, Caroline A., Norman, Michael R., McArdle, Craig A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2008
Schlagworte:
Mechanisms of Signal Transduction
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2546534/
https://ncbi.nlm.nih.gov/pubmed/18650424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M801500200
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