Pulsatile and Sustained Gonadotropin-releasing Hormone (GnRH) Receptor Signaling: DOES THE Ca(2+)/NFAT SIGNALING PATHWAY DECODE GnRH PULSE FREQUENCY?

Gonadotropin-releasing hormone (GnRH) acts via 7 transmembrane region receptors on gonadotrophs to stimulate synthesis and secretion of the luteinizing hormone and follicle-stimulating hormone. It is secreted in pulses, and its effects depend on pulse frequency, but decoding mechanisms are unknown....

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Hlavní autoři: Armstrong, Stephen P., Caunt, Christopher J., Fowkes, Robert C., Tsaneva-Atanasova, Krasimira, McArdle, Craig A.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2009
Témata:
Mechanisms of Signal Transduction
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2791005/
https://ncbi.nlm.nih.gov/pubmed/19858197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.063917
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