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Epidermal Growth Factor Receptor and Protein Kinase C Signaling to ERK2: SPATIOTEMPORAL REGULATION OF ERK2 BY DUAL SPECIFICITY PHOSPHATASES
Spatiotemporal aspects of ERK activation are stimulus-specific and dictate cellular consequences. They are dependent upon dual specificity phosphatases (DUSPs) that bind ERK via docking domains and can both inactivate and anchor ERK in cellular compartments. Using high throughput fluorescence micros...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2268109/ https://ncbi.nlm.nih.gov/pubmed/18178562 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M706624200 |
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