Dual specificity phosphatases 10 and 16 are positive regulators of EGF-stimulated ERK activity: Indirect regulation of ERK signals by JNK/p38 selective MAPK phosphatases

We have explored the possible role of dual specificity phosphatases (DUSPs) on acute EGF-mediated ERK signalling using high content imaging and a delayed MEK inhibition protocol to distinguish direct and indirect effects of the phosphatases on ERK activity. Using siRNAs, we were unable to find evide...

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Main Authors: Finch, Ann R., Caunt, Christopher J., Perrett, Rebecca M., Tsaneva-Atanasova, Krasimira, McArdle, Craig A.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier Science Ltd 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3314959/
https://ncbi.nlm.nih.gov/pubmed/22245064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2011.12.021
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