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Determination of thermodynamics and kinetics of RNA reactions by force

Single-molecule methods have made it possible to apply force to an individual RNA molecule. Two beads are attached to the RNA; one is on a micropipette, the other is in a laser trap. The force on the RNA and the distance between the beads are measured. Force can change the equilibrium and the rate o...

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Bibliografiske detaljer
Main Authors: Tinoco, Ignacio, Li, Pan T. X., Bustamante, Carlos
Format: Artigo
Sprog:Inglês
Udgivet: 2006
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2542947/
https://ncbi.nlm.nih.gov/pubmed/17040613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1017/S0033583506004446
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