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Unusual mechanical stability of a minimal RNA kissing complex

By using optical tweezers, we have investigated the mechanical unfolding of a minimal kissing complex with only two G·C base pairs. The loop–loop interaction is exceptionally stable; it is disrupted at forces ranging from 7 to 30 pN, as compared with 14–20 pN for unfolding hairpins of 7 and 11 bp. B...

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Detalhes bibliográficos
Main Authors: Li, Pan T. X., Bustamante, Carlos, Tinoco, Ignacio
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1635091/
https://ncbi.nlm.nih.gov/pubmed/17043221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0607202103
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