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The effect of force on thermodynamics and kinetics: unfolding single RNA molecules
We have used laser tweezers to unfold single RNA molecules at room temperature and in physiological-type solvents. The forces necessary to unfold the RNAs are over the range 10–20 pN, forces that can be generated by cellular enzymes. The Gibbs free energy for the unfolding of TAR (transactivation-re...
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| Main Authors: | , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2004
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1242187/ https://ncbi.nlm.nih.gov/pubmed/15494007 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BST0320757 |
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