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A two-state kinetic model for the unfolding of single molecules by mechanical force

We investigate the work dissipated during the irreversible unfolding of single molecules by mechanical force, using the simplest model necessary to represent experimental data. The model consists of two levels (folded and unfolded states) separated by an intermediate barrier. We compute the probabil...

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書誌詳細
主要な著者: Ritort, F., Bustamante, C., Tinoco, I.
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 2002
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC129710/
https://ncbi.nlm.nih.gov/pubmed/12374867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.172525099
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