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A two-state kinetic model for the unfolding of single molecules by mechanical force
We investigate the work dissipated during the irreversible unfolding of single molecules by mechanical force, using the simplest model necessary to represent experimental data. The model consists of two levels (folded and unfolded states) separated by an intermediate barrier. We compute the probabil...
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Hauptverfasser: | , , |
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Format: | Artigo |
Sprache: | Inglês |
Veröffentlicht: |
National Academy of Sciences
2002
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Schlagworte: | |
Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC129710/ https://ncbi.nlm.nih.gov/pubmed/12374867 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.172525099 |
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