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Force Unfolding Kinetics of RNA using Optical Tweezers. II. Modeling Experiments

By exerting mechanical force, it is possible to unfold/refold RNA molecules one at a time. In a small range of forces, an RNA molecule can hop between the folded and the unfolded state with force-dependent kinetic rates. Here, we introduce a mesoscopic model to analyze the hopping kinetics of RNA ha...

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Detalhes bibliográficos
Main Authors: Manosas, M., Wen, J.-D., Li, P. T. X., Smith, S. B., Bustamante, C., Tinoco, I., Ritort, F.
Formato: Artigo
Idioma:Inglês
Publicado em: Biophysical Society 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1852354/
https://ncbi.nlm.nih.gov/pubmed/17293409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.106.094243
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