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Probing the Mechanical Folding Kinetics of TAR RNA by Hopping, Force-Jump, and Force-Ramp Methods

Mechanical unfolding and refolding of single RNA molecules have previously been observed in optical traps as sudden changes in molecular extension. Two methods have been traditionally used: “force-ramp”, with the applied force continuously changing, and “hopping”. In hopping experiments the force is...

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Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Li, Pan T. X., Collin, Delphine, Smith, Steven B., Bustamante, Carlos, Tinoco, Ignacio
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Biophysical Society 2006
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1367024/
https://ncbi.nlm.nih.gov/pubmed/16214869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.105.068049
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