Probing the Mechanical Folding Kinetics of TAR RNA by Hopping, Force-Jump, and Force-Ramp Methods

Mechanical unfolding and refolding of single RNA molecules have previously been observed in optical traps as sudden changes in molecular extension. Two methods have been traditionally used: “force-ramp”, with the applied force continuously changing, and “hopping”. In hopping experiments the force is...

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Detaylı Bibliyografya
Asıl Yazarlar: Li, Pan T. X., Collin, Delphine, Smith, Steven B., Bustamante, Carlos, Tinoco, Ignacio
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Biophysical Society 2006
Konular:
Nucleic Acids
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1367024/
https://ncbi.nlm.nih.gov/pubmed/16214869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.105.068049
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