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Probing the Mechanical Folding Kinetics of TAR RNA by Hopping, Force-Jump, and Force-Ramp Methods
Mechanical unfolding and refolding of single RNA molecules have previously been observed in optical traps as sudden changes in molecular extension. Two methods have been traditionally used: “force-ramp”, with the applied force continuously changing, and “hopping”. In hopping experiments the force is...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Biophysical Society
2006
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1367024/ https://ncbi.nlm.nih.gov/pubmed/16214869 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.105.068049 |
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