Sulfatase 2 Up-Regulates Glypican 3, Promotes Fibroblast Growth Factor Signaling, and Decreases Survival in Hepatocellular Carcinoma

It has been shown that the heparin-degrading endosulfatase, sulfatase 1 (SULF1), functions as a liver tumor suppressor, but the role of the related sulfatase, sulfatase 2 (SULF2), in liver carcinogenesis remains to be elucidated. We investigated the effect of SULF2 on liver tumorigenesis. Expression...

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Hlavní autoři: Lai, Jin-Ping, Sandhu, Dalbir S., Yu, Chunrong, Han, Tao, Moser, Catherine D., Jackson, Kenard K., Guerrero, Ruben Bonilla, Aderca, Ileana, Isomoto, Hajime, Garrity-Park, Megan M., Zou, Hongzhi, Shire, Abdirashid M., Nagorney, David M., Sanderson, Schuyler O., Adjei, Alex A., Lee, Ju-Seog, Thorgeirsson, Snorri S., Roberts, Lewis R.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2536494/
https://ncbi.nlm.nih.gov/pubmed/18318435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.22202
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