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Inhibition of OXA-1 β-Lactamase by Penems

The partnering of a β-lactam with a β-lactamase inhibitor is a highly effective strategy that can be used to combat bacterial resistance to β-lactam antibiotics mediated by serine β-lactamases (EC 3.2.5.6). To this end, we tested two novel penem inhibitors against OXA-1, a class D β-lactamase that i...

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Bibliografische gegevens
Hoofdauteurs: Bethel, Christopher R., Distler, Anne M., Ruszczycky, Mark W., Carey, Marianne P., Carey, Paul R., Hujer, Andrea M., Taracila, Magda, Helfand, Marion S., Thomson, Jodi M., Kalp, Matthew, Anderson, Vernon E., Leonard, David A., Hujer, Kristine M., Abe, Takao, Venkatesan, Aranapakam M., Mansour, Tarek S., Bonomo, Robert A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology (ASM) 2008
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2533510/
https://ncbi.nlm.nih.gov/pubmed/18559643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01677-07
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