Survival and tumorigenesis in O(6)-methylguanine DNA methyltransferase-deficient mice following cyclophosphamide exposure

O(6)-methylguanine DNA methyltransferase (MGMT) deficiency is associated with an increased susceptibility to alkylating agent toxicity. To understand the contribution of MGMT in protecting against cyclophosphamide (CP)-induced toxicity, mutagenesis and tumorigenesis, we compared the biological effec...

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Bibliografski detalji
Glavni autori: Nagasubramanian, Ramamoorthy, Hansen, Ryan J., Delaney, Shannon M., Cherian, Mathew M., Samson, Leona D., Kogan, Scott C., Dolan, M. Eileen
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2008
Teme:
Original Articles
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2527341/
https://ncbi.nlm.nih.gov/pubmed/18477655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/mutage/gen018
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