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Mismatch repair proteins collaborate with methyltransferases in the repair of O(6)-methylguanine
DNA repair is essential for combatting the adverse effects of damage to the genome. One example of base damage is O(6)-methylguanine (O(6)mG), which stably pairs with thymine during replication and thereby creates a promutagenic O(6)mG:T mismatch. This mismatch has also been linked with cellular tox...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3015234/ https://ncbi.nlm.nih.gov/pubmed/17951114 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2007.09.003 |
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