Implication of Localization of Human DNA Repair Enzyme O(6)-Methylguanine-DNA Methyltransferase at Active Transcription Sites in Transcription-Repair Coupling of the Mutagenic O(6)-Methylguanine Lesion

DNA lesions that halt RNA polymerase during transcription are preferentially repaired by the nucleotide excision repair pathway. This transcription-coupled repair is initiated by the arrested RNA polymerase at the DNA lesion. However, the mutagenic O(6)-methylguanine (6MG) lesion which is bypassed b...

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Bibliographische Detailangaben
Hauptverfasser: Ali, Rahmen B., Teo, Alvin K.-C., Oh, Hue-Kian, Chuang, Linda S.-H., Ayi, Teck-Choon, Li, Benjamin F. L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 1998
Schlagworte:
DNA Dynamics and Chromosome Structure
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC108881/
https://ncbi.nlm.nih.gov/pubmed/9488483
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