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Enantioselective Total Synthesis of (+)-Gliocladin C

The first total synthesis of gliocladin C, a fungal-derived marine alkaloid containing a rare trioxopiperazine fragment, is reported. This asymmetric synthesis establishes the absolute configuration of this structurally novel natural product.

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Detalhes bibliográficos
Main Authors: Overman, Larry E., Shin, Youseung
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2526118/
https://ncbi.nlm.nih.gov/pubmed/17217299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol062801y
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