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Enantioselective Total Synthesis of Plectosphaeroic Acid B

The first total synthesis of a member of the plectosphaeroic acid family of fungal natural products is reported. Key steps include the late-stage formation of the hindered N6–C9″ bond and stereoselective introduction of the two methylthio substituents.

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Bibliographic Details
Main Authors: Jabri, Salman Y., Overman, Larry E.
Format: Artigo
Language:Inglês
Published: 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3611964/
https://ncbi.nlm.nih.gov/pubmed/23452064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja401423j
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