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Enantioselective Total Synthesis of Batzelladine F and Definition of Its Structure

Batzelladine F (1) was synthesized in enantioselective and stereoselective fashion in 15 steps (longest linear sequence) and 1.7% overall yield from two readily available enantioenriched β-hydroxy esters, methyl (R)-3-hydroxydecanoate and methyl (R)-3-hydroxybutyrate. Tethered Biginelli condensation...

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Detalhes bibliográficos
Main Authors: Cohen, Frederick, Overman, Larry E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2535800/
https://ncbi.nlm.nih.gov/pubmed/16492044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja057433s
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