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A Random shRNA-Encoding Library for Phenotypic Selection and Hit-Optimization
RNA interference (RNAi) is a mechanism for inhibiting gene expression through the action of small, non-coding RNAs. Most existing RNAi libraries target single genes through canonical pathways. Endogenous microRNAs (miRNAs), however, often target multiple genes and can act through non-canonical pathw...
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| Auteurs principaux: | , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Public Library of Science
2008
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2525836/ https://ncbi.nlm.nih.gov/pubmed/18779859 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0003171 |
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