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Pooled shRNA Library Screening to Identify Factors that Modulate a Drug Resistance Phenotype

Understanding clinically relevant driver mechanisms of acquired chemo-resistance is crucial for elucidating ways to circumvent resistance and improve survival in patients with acute myeloid leukemia (AML). A small fraction of leukemic cells that survive chemotherapy have a poised epigenetic state to...

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Detalhes bibliográficos
Publicado no:J Vis Exp
Main Authors: Das, Saswati, Stallon Illangeswaran, Raveen Stephen, Ijee, Smitha, Kumar, Sanjay, Velayudhan, Shaji Ramachandran, Balasubramanian, Poonkuzhali
Formato: Artigo
Idioma:Inglês
Publicado em: 2022
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7614927/
https://ncbi.nlm.nih.gov/pubmed/35786700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/63383
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