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Pooled shRNA Library Screening to Identify Factors that Modulate a Drug Resistance Phenotype
Understanding clinically relevant driver mechanisms of acquired chemo-resistance is crucial for elucidating ways to circumvent resistance and improve survival in patients with acute myeloid leukemia (AML). A small fraction of leukemic cells that survive chemotherapy have a poised epigenetic state to...
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| Vydáno v: | J Vis Exp |
|---|---|
| Hlavní autoři: | , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2022
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7614927/ https://ncbi.nlm.nih.gov/pubmed/35786700 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/63383 |
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