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Systems analysis of quantitative shRNA-library screens identifies regulators of cell adhesion

BACKGROUND: High throughput screens with RNA interference technology enable loss-of-function analyses of gene activities in mammalian cells. While the construction of genome-scale shRNA libraries has been successful, results of large-scale screening of those libraries can be difficult to analyze bec...

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Detalhes bibliográficos
Main Authors: Huang, XiaoDong, Wang, Jean YJ, Lu, Xin
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2441606/
https://ncbi.nlm.nih.gov/pubmed/18549508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1752-0509-2-49
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