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shRNA target prediction informed by comprehensive enquiry (SPICE): a supporting system for high-throughput screening of shRNA library

RNA interference (RNAi) screening is extensively used in the field of reverse genetics. RNAi libraries constructed using random oligonucleotides have made this technology affordable. However, the new methodology requires exploration of the RNAi target gene information after screening because the RNA...

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Detalles Bibliográficos
Publicado en:EURASIP J Bioinform Syst Biol
Main Authors: Kamatuka, Kenta, Hattori, Masahiro, Sugiyama, Tomoyasu
Formato: Artigo
Idioma:Inglês
Publicado: Springer International Publishing 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4761003/
https://ncbi.nlm.nih.gov/pubmed/26941783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13637-016-0039-8
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