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A primer on using pooled shRNA libraries for functional genomic screens
The discovery of RNA interference (RNAi) has revolutionized genetic analysis in mammalian cells. Loss-of-function RNAi screens enable rapid, functional annotation of the genome. Of the various RNAi approaches, pooled shRNA libraries have received considerable attention because of their versatility....
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2012
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| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3263926/ https://ncbi.nlm.nih.gov/pubmed/22271906 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/abbs/gmr116 |
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