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A primer on using pooled shRNA libraries for functional genomic screens

The discovery of RNA interference (RNAi) has revolutionized genetic analysis in mammalian cells. Loss-of-function RNAi screens enable rapid, functional annotation of the genome. Of the various RNAi approaches, pooled shRNA libraries have received considerable attention because of their versatility....

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Sonraí Bibleagrafaíochta
Main Authors: Hu, Guang, Luo, Ji
Formáid: Artigo
Teanga:Inglês
Foilsithe: Oxford University Press 2012
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3263926/
https://ncbi.nlm.nih.gov/pubmed/22271906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/abbs/gmr116
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