DNA hypermethylation and epigenetic silencing of the tumor suppressor gene, SLC5A8, in acute myeloid leukemia with the MLL partial tandem duplication

Posttranslationally modified histones and DNA hypermethylation frequently interplay to deregulate gene expression in cancer. We report that acute myeloid leukemia (AML) with an aberrant histone methyltransferase, the mixed lineage leukemia partial tandem duplication (MLL-PTD), exhibits increased glo...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Whitman, Susan P., Hackanson, Björn, Liyanarachchi, Sandya, Liu, Shujun, Rush, Laura J., Maharry, Kati, Margeson, Dean, Davuluri, Ramana, Wen, Jing, Witte, Tatiana, Yu, Li, Liu, Chunhui, Bloomfield, Clara D., Marcucci, Guido, Plass, Christoph, Caligiuri, Michael A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2008
Assuntos:
Neoplasia
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2518901/
https://ncbi.nlm.nih.gov/pubmed/18566324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-01-128595
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados