Mll partial tandem duplication induces aberrant Hox expression in vivo via specific epigenetic alterations

We previously identified a rearrangement of mixed-lineage leukemia (MLL) gene (also known as ALL-1, HRX, and HTRX1), consisting of an in-frame partial tandem duplication (PTD) of exons 5 through 11 in the absence of a partner gene, occurring in approximately 4%–7% of patients with acute myeloid leuk...

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Bibliografiska uppgifter
Huvudupphovsmän: Dorrance, Adrienne M., Liu, Shujun, Yuan, Weifeng, Becknell, Brian, Arnoczky, Kristy J., Guimond, Martin, Strout, Matthew P., Feng, Lan, Nakamura, Tatsuya, Yu, Li, Rush, Laura J., Weinstein, Michael, Leone, Gustavo, Wu, Lizhao, Ferketich, Amy, Whitman, Susan P., Marcucci, Guido, Caligiuri, Michael A.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Clinical Investigation 2006
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1564428/
https://ncbi.nlm.nih.gov/pubmed/16981007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI25546
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