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Mll partial tandem duplication induces aberrant Hox expression in vivo via specific epigenetic alterations
We previously identified a rearrangement of mixed-lineage leukemia (MLL) gene (also known as ALL-1, HRX, and HTRX1), consisting of an in-frame partial tandem duplication (PTD) of exons 5 through 11 in the absence of a partner gene, occurring in approximately 4%–7% of patients with acute myeloid leuk...
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| Huvudupphovsmän: | , , , , , , , , , , , , , , , , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
American Society for Clinical Investigation
2006
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1564428/ https://ncbi.nlm.nih.gov/pubmed/16981007 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI25546 |
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