Mll partial tandem duplication induces aberrant Hox expression in vivo via specific epigenetic alterations

We previously identified a rearrangement of mixed-lineage leukemia (MLL) gene (also known as ALL-1, HRX, and HTRX1), consisting of an in-frame partial tandem duplication (PTD) of exons 5 through 11 in the absence of a partner gene, occurring in approximately 4%–7% of patients with acute myeloid leuk...

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Detalhes bibliográficos
Main Authors: Dorrance, Adrienne M., Liu, Shujun, Yuan, Weifeng, Becknell, Brian, Arnoczky, Kristy J., Guimond, Martin, Strout, Matthew P., Feng, Lan, Nakamura, Tatsuya, Yu, Li, Rush, Laura J., Weinstein, Michael, Leone, Gustavo, Wu, Lizhao, Ferketich, Amy, Whitman, Susan P., Marcucci, Guido, Caligiuri, Michael A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2006
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1564428/
https://ncbi.nlm.nih.gov/pubmed/16981007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI25546
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