The Mll partial tandem duplication: differential, tissue-specific activity in the presence or absence of the wild-type allele

Eitemau Tebyg

• Mll partial tandem duplication induces aberrant Hox expression in vivo via specific epigenetic alterations
  gan: Dorrance, Adrienne M., et al.
  Cyhoeddwyd: (2006)
• The MLL partial tandem duplication: evidence for recessive gain-of-function in acute myeloid leukemia identifies a novel patient subgroup for molecular-targeted therapy
  gan: Whitman, Susan P., et al.
  Cyhoeddwyd: (2005)
• Mll partial tandem duplication and Flt3 internal tandem duplication in a double knock-in mouse recapitulates features of counterpart human acute myeloid leukemias
  gan: Zorko, Nicholas A., et al.
  Cyhoeddwyd: (2012)
• DNA hypermethylation and epigenetic silencing of the tumor suppressor gene, SLC5A8, in acute myeloid leukemia with the MLL partial tandem duplication
  gan: Whitman, Susan P., et al.
  Cyhoeddwyd: (2008)
• The partial tandem duplication of ALL1 (MLL) is consistently generated by Alu-mediated homologous recombination in acute myeloid leukemia
  gan: Strout, Matthew P., et al.
  Cyhoeddwyd: (1998)