Relative value of ZAP-70, CD38, and immunoglobulin mutation status in predicting aggressive disease in chronic lymphocytic leukemia

Leukemia-cell expression of ZAP-70, CD38, or unmutated immunoglobulin heavy chain variable region genes (U-IGHV) each is associated with aggressive disease in patients with chronic lymphocytic leukemia (CLL). To assess the relative strength of each marker, we defined thresholds for designating a cas...

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Autori principali: Rassenti, Laura Z., Jain, Sonia, Keating, Michael J., Wierda, William G., Grever, Michael R., Byrd, John C., Kay, Neil E., Brown, Jennifer R., Gribben, John G., Neuberg, Donna S., He, Feng, Greaves, Andrew W., Rai, Kanti R., Kipps, Thomas J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Hematology 2008
Soggetti:
Neoplasia
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2518894/
https://ncbi.nlm.nih.gov/pubmed/18577710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-05-092882
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