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ZAP-70 enhances IgM signaling independent of its kinase activity in chronic lymphocytic leukemia

We transduced chronic lymphocytic leukemia (CLL) cells lacking ZAP-70 with vectors encoding ZAP-70 or various mutant forms of ZAP-70 and monitored the response of transduced CLL cells to treatment with F(ab)(2) anti-IgM (anti-μ). CLL cells made to express ZAP-70, a kinase-defective ZAP-70 (ZAP-70-KA...

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Detalhes bibliográficos
Main Authors: Chen, Liguang, Huynh, Lang, Apgar, John, Tang, Li, Rassenti, Laura, Weiss, Arthur, Kipps, Thomas J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2254551/
https://ncbi.nlm.nih.gov/pubmed/18048647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2006-12-062265
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