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ZAP-70 enhances IgM signaling independent of its kinase activity in chronic lymphocytic leukemia
We transduced chronic lymphocytic leukemia (CLL) cells lacking ZAP-70 with vectors encoding ZAP-70 or various mutant forms of ZAP-70 and monitored the response of transduced CLL cells to treatment with F(ab)(2) anti-IgM (anti-μ). CLL cells made to express ZAP-70, a kinase-defective ZAP-70 (ZAP-70-KA...
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| Hauptverfasser: | , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society of Hematology
2008
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2254551/ https://ncbi.nlm.nih.gov/pubmed/18048647 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2006-12-062265 |
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