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Replication-coupled repair of crotonaldehyde/acetaldehyde-induced guanine-guanine interstrand cross-links and their mutagenicity

The repair of acetaldehyde/crotonaldehyde-induced guanine(N(2))-guanine(N(2)) interstrand cross-links (ICLs), 3-(2-deoxyribos-1-yl)-5,6,7,8-(N(2)-deoxyguanosyl)-6(R or S)-methyl-pyrimido[1,2-α]purine-10(3H)one (Scheme 1), was studied using a shuttle plasmid bearing a site-specific ICL. Since the aut...

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Bibliografiske detaljer
Main Authors: Liu, Xiang, Lao, Yanbin, Yang, In-Young, Hecht, Stephen S., Moriya, Masaaki
Format: Artigo
Sprog:Inglês
Udgivet: 2006
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2518849/
https://ncbi.nlm.nih.gov/pubmed/17042508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi060792v
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