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Mutagenic Repair of DNA Interstrand Crosslinks

Formation of DNA interstrand crosslinks (ICLs) in chromosomal DNA imposes acute obstruction of all essential DNA functions. For nearly a century, bifunctional alkylators, also known as DNA crosslinkers, have been an important class of cancer chemotherapeutic regimens. The mechanisms of ICL repair re...

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Hlavní autoři: Shen, Xi, Li, Lei
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2892553/
https://ncbi.nlm.nih.gov/pubmed/20209624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/em.20558
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