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Mutagenic Repair of DNA Interstrand Crosslinks
Formation of DNA interstrand crosslinks (ICLs) in chromosomal DNA imposes acute obstruction of all essential DNA functions. For nearly a century, bifunctional alkylators, also known as DNA crosslinkers, have been an important class of cancer chemotherapeutic regimens. The mechanisms of ICL repair re...
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2892553/ https://ncbi.nlm.nih.gov/pubmed/20209624 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/em.20558 |
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