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DNA INTERSTRAND CROSSLINK REPAIR IN MAMMALIAN CELLS: STEP BY STEP

Interstrand DNA crosslinks (ICLs) are formed by natural products of metabolism and by chemotherapeutic reagents. Work in E. coli identified a two cycle repair scheme involving incisions on one strand on either side of the ICL (unhooking) producing a gapped intermediate with the incised oligonucleoti...

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Detalhes bibliográficos
Main Authors: Muniandy, Parameswary, Liu, Jia, Majumdar, Alokes, Liu, Su-ting, Seidman, Michael M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2824768/
https://ncbi.nlm.nih.gov/pubmed/20039786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/10409230903501819
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