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Single Molecule Analysis of Laser Localized Interstrand Crosslinks
DNA interstrand crosslinks (ICLs) block unwinding of the double helix, and have always been regarded as major challenges to replication and transcription. Compounds that form these lesions are very toxic and are frequently used in cancer chemotherapy. We have developed two strategies, both based on...
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| Publicado no: | Front Genet |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4860505/ https://ncbi.nlm.nih.gov/pubmed/27242893 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2016.00084 |
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