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Single Molecule Analysis of Laser Localized Interstrand Crosslinks
DNA interstrand crosslinks (ICLs) block unwinding of the double helix, and have always been regarded as major challenges to replication and transcription. Compounds that form these lesions are very toxic and are frequently used in cancer chemotherapy. We have developed two strategies, both based on...
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| Izdano u: | Front Genet |
|---|---|
| Glavni autori: | , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Frontiers Media S.A.
2016
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4860505/ https://ncbi.nlm.nih.gov/pubmed/27242893 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2016.00084 |
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