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Repair of Laser-localized DNA Interstrand Cross-links in G(1) Phase Mammalian Cells
Interstrand cross-links (ICLs) are absolute blocks to transcription and replication and can provoke genomic instability and cell death. Studies in bacteria define a two-stage repair scheme, the first involving recognition and incision on either side of the cross-link on one strand (unhooking), follo...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society for Biochemistry and Molecular Biology
2009
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2788842/ https://ncbi.nlm.nih.gov/pubmed/19684342 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.029025 |
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