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Cross-Link Structure Affects Replication-Independent DNA Interstrand Cross-Link Repair in Mammalian Cells
DNA interstrand cross-links (ICLs) are cytotoxic products of common anti-cancer drugs and cellular metabolic processes, whose mechanism(s) of repair remain poorly understood. In this study, we show that cross-link structure affects ICL repair in non-replicating reporter plasmids that contain a mispa...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2864352/ https://ncbi.nlm.nih.gov/pubmed/20373772 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi902169q |
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