טוען...

Facile Detection of Acyl- and Peptidyl- intermediates on Thiotemplate Carrier Domains via Phosphopantetheinyl Elimination Reactions During Tandem Mass Spectrometry

With the emergence of drug resistance and the genomic revolution there has been a renewed interest in the genes that are responsible for the generation of bioactive natural products. Secondary metabolites of one major class are biosynthesized at one or more sites by ultra large enzymes that carry co...

תיאור מלא

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מידע ביבליוגרפי
Main Authors: Dorrestein, Pieter C., Bumpus, Stefanie B., Calderone, Christopher T., Garneau-Tsodikova, Sylvie, Aron, Zachary D., Straight, Paul D., Kolter, Roberto, Walsh, Christopher T., Kelleher, Neil L.
פורמט: Artigo
שפה:Inglês
יצא לאור: 2006
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2518290/
https://ncbi.nlm.nih.gov/pubmed/17042494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi061169d
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