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Accessing Natural Product Biosynthetic Processes by Mass Spectrometry (Truncated Title: MS Analysis of Thiotemplate Biosynthesis)

Two important classes of natural products are made by non-ribosomal peptide synthetases (NRPSs) and polyketide synthases (PKSs). With most biosynthetic intermediates covalently tethered during biogenesis, protein mass spectrometry (MS) has proven invaluable for their interrogation. New mass spectrom...

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Detalhes bibliográficos
Main Authors: Bumpus, Stefanie B., Kelleher, Neil L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2642909/
https://ncbi.nlm.nih.gov/pubmed/18706516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbpa.2008.07.022
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