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Modern mass spectrometry for synthetic biology and structure-based discovery of natural products

In this highlight, we describe the current landscape for dereplication and discovery of natural products based on the measurement of the intact mass by LC-MS. Often it is assumed that because better mass accuracy (provided by higher resolution mass spectrometers) is necessary for absolute chemical f...

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Библиографические подробности
Опубликовано в: :Nat Prod Rep
Главные авторы: Henke, Matthew T., Kelleher, Neil L.
Формат: Artigo
Язык:Inglês
Опубликовано: 2016
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4981503/
https://ncbi.nlm.nih.gov/pubmed/27376415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c6np00024j
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