Combined transgenic expression of α-galactosidase and α1,2-fucosyltransferase leads to optimal reduction in the major xenoepitope Galα(1,3)Gal

Samankaltaisia teoksia

• Trichostatin A-Assisted Epigenomic Modulation Affects the Expression Profiles of Not Only Recombinant Human α1,2-Fucosyltransferase and α-Galactosidase A Enzymes But Also Galα1→3Gal Epitopes in Porcine Bi-Transgenic Adult Cutaneous Fibroblast Cells
  Tekijä: Wiater, Jerzy, et al.
  Julkaistu: (2021)
• Double Transgenic Pigs with Combined Expression of Human α1,2-Fucosyltransferase and α-Galactosidase Designed to Avoid Hyperacute Xenograft Rejection
  Tekijä: Zeyland, Joanna, et al.
  Julkaistu: (2014)
• Reduction in the level of Gal(alpha1,3)Gal in transgenic mice and pigs by the expression of an alpha(1,2)fucosyltransferase.
  Tekijä: Sharma, A, et al.
  Julkaistu: (1996)
• Fabry Disease: Preclinical Studies Demonstrate the Effectiveness of α-Galactosidase A Replacement in Enzyme-Deficient Mice
  Tekijä: Ioannou, Yiannis A., et al.
  Julkaistu: (2001)
• Anti-pig IgM antibodies in human serum react predominantly with Gal(alpha 1-3)Gal epitopes.
  Tekijä: Sandrin, M S, et al.
  Julkaistu: (1993)