Anti-pig IgM antibodies in human serum react predominantly with Gal(alpha 1-3)Gal epitopes.
A major problem with pig-to-human-tissue xenograft studies is that humans have natural antibodies to pig cells; these antibodies would cause hyperacute rejection if pig tissues were xenografted to humans. Here we show that most of human IgM antibodies present in the serum of healthy donors and react...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1993
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC47988/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7504304/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.23.11391 |
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