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Anti-pig IgM antibodies in human serum react predominantly with Gal(alpha 1-3)Gal epitopes.

A major problem with pig-to-human-tissue xenograft studies is that humans have natural antibodies to pig cells; these antibodies would cause hyperacute rejection if pig tissues were xenografted to humans. Here we show that most of human IgM antibodies present in the serum of healthy donors and react...

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Bibliografiset tiedot
Päätekijät: Sandrin, M S, Vaughan, H A, Dabkowski, P L, McKenzie, I F
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 1993
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC47988/
https://ncbi.nlm.nih.gov/pubmed/7504304
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