Yüklüyor......
Direct and Potent Regulation of γ-Secretase by Its Lipid Microenvironment
γ-Secretase is an unusual and ubiquitous aspartyl protease with an intramembrane catalytic site that cleaves many type-I integral membrane proteins, most notably APP and Notch. Several reports suggest that cleavage of APP to produce the Aβ peptide is regulated in part by lipids. As γ-secretase is a...
Kaydedildi:
| Asıl Yazarlar: | , , , , |
|---|---|
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
American Society for Biochemistry and Molecular Biology
2008
|
| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2504869/ https://ncbi.nlm.nih.gov/pubmed/18539594 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M801925200 |
| Etiketler: |
Etiketle
Etiket eklenmemiş, İlk siz ekleyin!
|