A carregar...
Part 1: Notch-Sparing γ-Secretase Inhibitors: The Identification of Novel Naphthyl and Benzofuranyl Amide Analogs
γ-Secretase is one of two proteases directly involved in the production of the amyloid β-peptide, (Aβ) which is pathogenic in Alzheimer’s disease. Inhibition of γ-secretase to suppress the production of Aβ should not block processing of one of its alternative substrates, Notch1 receptors, as interfe...
Na minha lista:
| Publicado no: | Bioorg Med Chem Lett |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8317589/ https://ncbi.nlm.nih.gov/pubmed/27013392 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2016.03.040 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|