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Glu-333 of Nicastrin Directly Participates in γ-Secretase Activity
γ-Secretase is a proteolytic membrane complex that processes a variety of substrates including the amyloid precursor protein and the Notch receptor. Earlier we showed that one of the components of this complex, nicastrin (NCT), functions as a receptor for γ-secretase substrates. A recent report chal...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society for Biochemistry and Molecular Biology
2009
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2785603/ https://ncbi.nlm.nih.gov/pubmed/19729449 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.038737 |
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